Knightley is the face of an Amnesty International campaign to support human rights, marking the 60th anniversary of the United Nation's Universal Declaration of Human Rights. As part of the campaign, the star also made a short film. Knightley stated she wanted to help raise awareness of the UDHR and human rights abuses. said "The UDHR is something that everyone should be aware of and be proud of as a statement of our common humanity."
Knightley contributed her voice to a 2007 Robbie the Reindeer animation, all profits of which will be donated to Comic Relief. In 2004, she travelled to Ethiopia with a group that included Richard Curtis, who had directed her in Love, Actually, on behalf of that charity.
In April 2009, Knightley appeared in a video to raise awareness of domestic abuse entitled Cut. The video was directed by Joe Wright, who directed Knightley in Pride and Prejudice and Atonement, and shot for "Women's Aid," a British women and children aid group. The video has created controversy, with some sources calling it too graphic, while other groups support the video for showing a realistic depiction of domestic violence.
In November 2010, Knightley became patron of The SMA Trust, a British charity that funds medical research into the children's disease Spinal Muscular Atrophy.
In March 2011, she appeared briefly in the Smithy sketch for Red Nose Day 2011, alongside Sir Paul McCartney, former Prime Minister Gordon Brown, Davina McCall, Justin Bieber and JLS, amongst others
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